Journal of Liver Cancer

Kun Hoon Song

3 Articles

A Case of Hepatocellular Carcinoma with Bile Duct Invasion: Seung Min Bang, Hye Won Chung, Jae Youn Cheong, Chung Ryul Lee, Kun Hoon Song, Kwang Hyub Han, Chae Yoon Cheon, Young Myoung Moon, Sung Il Park, Do Yun Lee, Jong Tae Lee; Journal of the Korean Liver Cancer Study Group. 2001;1(1):85-88. Published online June 30, 2001

Abstract PDF: A 52 year-old female patient with liver cirrhosis admitted due to icteric skin color for 3 weeks. Four months ago, she had been diagnosed as hepatocellular carcinoma(HCC), and treated with transarterial chemoembolization(TACE) at another hospital. Physical findings revealed that she had icteric sclera without ascites or palpable hepatosplenomegaly. Total bilirubin was 6.0mg/dL, ALT/AST was 117/111 IU/L. Computed tomography showed 3cm sized nodular mass involving left lateral segment of the liver and left intrahepatic bile duct. Endoscopic retrograde cholangiopancreatography(ERCP) revealed filling defect of left intrahepaitc duct and common hepatic duct, suggesting left intrahepatic duct and common hepatic duct invasion of HCC. After endoscopic retrograde biliary drainage(ERBD) with stent insertion, total bilirubin was decreased and clinical symptoms were improved. She was treated with TACE using adriamycin after ERBD. Thereafter, she was prescribed oral 5-fluorouracil and treated with external radiotherapy(4,500cGy). Five months later after the treatment, CT scan showed decrease in tumor size, and jaundice was improved as well.

A Case of Hepatocellular Carcinoma with Dramatic Therapeutic Response in Stage Ⅳa (T4N0M0): Hye Won Chung, Jae Youn Cheong, Kun Hoon Song, Kwang Hyub Han, Young Myoung Moon, Byoung Ro Kim, Jin Sil Seong, Myoung Jin Kim, Do Yun Lee, Young Nyun Park; Journal of the Korean Liver Cancer Study Group. 2001;1(1):89-92. Published online June 30, 2001

Abstract PDF: A 52 year-old-female patient was admitted due to right upper quadrant abdominal pain and right shoulder pain for 1 month. She had no history of previous medical problem before admission. At admission, physical findings revealed that she had 2 FB palpable hepatomegaly and others were not remarkable. Laboratory findings revealed that HBsAg and HBeAG were positive enhanced at arterial phase involving entire right lobe and S4, and thrombus at main portal vein. Clinically she was diagnosed advanced hepatocellular carcinoma(HCC) and TNM stage was T4N0M0, stage Ⅳa. She was treated with transarterial chemoembolization(TACE) for 2 cycles and radiation therapy. After TACE and radiation therapy, the tumor size decreased and the main portal vein thrombus was disappeared. Then, she underwent extended right lobectomy of the liver. Pathology of operative specimen revealed well-encapsulated HCC at Edmonsons grade Ⅱ, near total necrosis. Normal liver tissue showed sinusoidal congestion, mild periportal fibrosis, and veno-occlusive disease. Two years after the operation, there had been no sign of recurrence and follow-up CT scan showed sign of recurrence at S2. He underwent percutaneous Holmium injection 3 times and TACE 4 times, and so far he survived for 6 years and 10 months. He is currently under observation at out patient department.

A Case of Hepatocellular Carcinoma with Right Adrenal Gland Metastasis Treated with Left Lobectomy and Right Adrenalectomy: Young Joon Yoon, Chae Yoon Chon, Chul Kim, Kun Hoon Song, Jae Yeon Jung, Kwang Hyub Han, Young Myung Moon, Do Yun Lee, Jong Tae Lee; Journal of the Korean Liver Cancer Study Group. 2001;1(1):114-117. Published online June 30, 2001

Abstract PDF: A 42 year-old-female patient with hepatocellular carcinoma was admitted. A year and half ago, she had been diagnosed as having hepatocellular carcinoma(HCC), and treated with transarterial chemoembolization(TACE). Seven months later, Abdomen CT showed recurrence of previously treated HCC and right adrenal gland metastasis. A hepatic angiography demonstrated faint nodule in left lobe of the liver, which was treated with transarterial chemoinfusion(TACI). Right renal angiography demonstrated right adrenal gland mass standing but the embolization was impossible due to narrow vessel caliber. She was treated with total 5,460cGy radiotherapy for right adrenal gland. She was treated with TACI for HCC once more before admission. Total bilirubin was 0.2 mg/dl, AST/ALT, 30/25 IU/L, albumin, 3.8 g/dl, and PT, 100%. AFP was markedly increased to 18,870 ng/ml compared with 6,746 ng/ml at the time of diagnosis. CT demonstrated no interval change of previously treated hepatocellular carcinoma in left lobe of the liver but increased size of right adrenal mass. She was treated with left lobectomy and right adrenalectomy. Postoperative CT demonstrated no evidence of recurrence and AFP was reduced to 257.8 ng/ml. She was then treated with systemic chemotherapy with adriamycin ten times. After the end of treatment, AFP was reduced to 1.64 ng/ml.